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Orbital infarction syndrome is defined as ischemia of all intraorbital and
intraocular structures. It is a rare disease caused by rich anastomotic
vascularization of the orbit. It can occur secondary to different conditions,
such as, acute perfusion failure, systemic vasculitis, orbital cellulitis and
vasculitis. It results in orbital and ocular pain, total ophthalmoplegia,
anterior and posterior segment ischemia, and acute blindness. We report here
upon two cases of orbital infarction with similar presentations but with
different causes, namely, mucormycosis and as a postoperative complication of
intracranial aneurysm, discuss the possible mechanisms of orbital infarction,
and present a review of the literature on the topic. The prompt recognition of
clinical pictures and rapid diagnosis is essential for the early treatment of
orbital infarction, since its progression is very rapid and it can be even
fatal.