Korean J Radiol.  2002 Jun;3(2):133-135. 10.3348/kjr.2002.3.2.133.

Radiologic Findings of Multiple Myeloma with Gastric Involvement: A Case Report

• Kwak HS
• Jin GY
• Lee JM

• KMID: 754073
• DOI: http://doi.org/10.3348/kjr.2002.3.2.133

Abstract

We report a case of multiple myeloma with gastric involvement occurring in a patient who underwent an upper gastrointestinal series (UGIS), CT and MRI. UGIS depicted a luminal protruding mass, while contrast-enhanced CT demonstrated marked thickening of the gastric wall, with subtle contrast enhancement. At T1- and T2-weighted MR imaging, the mass showed iso- and intermediate signal intensity, respectively. After the administration of contrast material, subtle homogeneous enhancement was apparent.

Keyword

Stomach, neoplasms; Stomach, radiography; Stomach, magnetic resonance imaging; Stomach, CT

MeSH Terms

Case Report
Contrast Media/administration & dosage
Human
Magnetic Resonance Imaging
Male
Middle Age
Multiple Myeloma/pathology/*radiography
Stomach Neoplasms/pathology/*radiography
Tomography, X-Ray Computed

Figure

• 

  Fig. 1 Multiple myeloma with gastric involvement in a 61-year-old man. A. Upper gastrointestinal series shows a large, protruding, luminal mass (arrows) with a well-defined margin in the anterior wall of the gastric cardia. B. Contrast-enhanced CT scan demonstrates marked gastric wall thickening with subtle contrast enhancement (arrows). C. Axial T2-weighted image shows homogeneous signal intensity slightly higher than that of the liver (arrows). D. Axial gadolinium-enhanced MR image obtained 3 minutes after the administration of contrast material depicts homogeneous enhancement, similar to that of hepatic parenchyma. E. Photograph of endoscopic biopsy specimen shows dense and monotonous infiltration by plasma cells (original magnification, ×200; hematoxylin-eosin staining). Note the presence of a monomorphic population of plasma cells with variable atypia.

Reference

1. Kinoshita Y, Watanabe M, Takahashi H, et al. A case of gastric plasmacytoma: genetic analysis and immunofixation electrophoresis. Am J Gastroenterol. 1991. 86:349–353.

2. Spagnoli I, Gattoni F, Mazzoni R, Uslenghi C. Primary gastrointestinal plasmacytoma: report of three cases. Diagn Imaging. 1983. 52:23–27.

3. Yoon SE, Ha HK, Lee YS, et al. Upper gastrointestinal series and CT findings of primary gastric plasmacytoma: report of two cases. AJR. 1999. 173:1266–1268.

4. Pimental RR, Van Stolk R. Gastric plasmacytoma: a rare cause of massive gastrointestinal bleeding. Am J Gastroenterol. 1993. 88:1963–1964.

5. Remingio PA, Klaum A. Extramedullary plasmacytoma of the stomach. Cancer. 1971. 27:562–568.

6. Marcos HB, Semelka RC. Stomach diseases: MR evaluation using combined T2-weighted single-shot echo train spin-echo and gadolinium-enhanced spoiled gradient-echo sequences. J Magn Reson Imaging. 1999. 10:950–960.