Yonsei Med J.  1999 Oct;40(5):450-453. 10.3349/ymj.1999.40.5.450.

A decrease in circulating levels of immunoreactive insulin-like growth factor binding protein-1 (IGFBP-1) after endometrial ablation using a gynecologicresectoscope

Affiliations
  • 1Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea. jny6693@yumc.yonsei.ac.kr
  • 2Department of Obstetrics and Gynecology, Yongdong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Obstetrics and Gynecology, Kangbuk Samsung Hospital, Seoul, Korea.

Abstract

To determine how endometrium alone would contribute to maintaining the circulating levels of Insulin-like growth factor binding protein-1 in vivo, serum immunoreactive IGFBP-1 levels were measured in 19 patients undergoing endometrial ablation using gynecologic resectoscopy. After endometrial ablation there was a significant decrease in the mean levels of circulating IGFBP-1, which was not correlated with the menstrual cycle. This result indicates that the endometrium is one of the sources of the circulating IGFBP-1.

Keyword

Insulin-like growth factor binding protein-1; endometrial ablation

MeSH Terms

Adult
Endometrium/surgery*
Endoscopes
Female
Human
Insulin-Like Growth-Factor Binding Protein 1/blood*
Menstruation
Middle Age
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