J Korean Med Sci.  2001 Aug;16(4):505-508. 10.3346/jkms.2001.16.4.505.

A Case of Disseminated Trichosporon beigelii Infection in a Patient with Myelodysplastic Syndrome after Chemotherapy

• Kim JC
• Kim YS
• Park CS
• Kang JM
• Kim BN
• Woo JH
• Ryu J
• Kim WG

• KMID: 648311
• DOI: http://doi.org/10.3346/jkms.2001.16.4.505

Abstract

Trichosporonosis is a potentially life-threatening infection with Trichosporon beigelii, the causative agent of white piedra. The systemic infection by this fungus has been most frequently described in immunocompromised hosts with neutropenia. Here, we report the first patient with disseminated infection by T. beigelii in Korea, acquired during a period of severe neutropenia after chemo-therapy for myelodysplastic syndrome. The patient recovered from the infection after an early-intensified treatment with amphotericin B and a rapid neutrophil recovery. The disseminated infection by T. beigelii is still rare, however, is an emerging fatal mycosis in immunocompromised patients with severe neutropenia.

Keyword

Trichosporon; Immunocompromised Host; Myelodysplastic Syndromes; Amphotericin B

MeSH Terms

Adult
Amphotericin B/therapeutic use
Human
Male
Mycoses/drug therapy/*etiology
Myelodysplastic Syndromes/*complications/drug therapy