J Korean Med Sci.  1995 Apr;10(2):93-96. 10.3346/jkms.1995.10.2.93.

Differentiation of malignant from benign pancreatic mass by Tl-201 abdominal SPECT

• Bom HS
• Song HC
• Kim JY
• Choi SK
• Rew JS
• Yoon CM

• KMID: 644860
• DOI: http://doi.org/10.3346/jkms.1995.10.2.93

Abstract

The aim of the present study was to evaluate the ability of Tl-201 abdominal SPECT to differentiate between chronic focal pancreatitis and pancreatic malignancy. Seventeen patients (12 men, 5 women; mean age, 56 years; 9 pancreatic cancer, 8 chronic pancreatitis) with pancreatic mass were prospectively investigated with Tl-201 abdominal SPECT. In all patients, CT and/or US could not clarify the nature of the pancreatic mass. Focal hot uptake was present in 8 of 9 patients with pancreatic cancer, while it was present in 2 of 8 patients with chronic pancreatitis. Therefore, the sensitivity and specificity of the present study were 89% and 75%, respectively. A significant difference of Tl-201 uptakes was noted between benign and malignant masses (p& 0.05). Therefore, we concluded that Tl-201 abdominal SPECT was a useful test in differentiation of malignant from benign pancreatic mass, especially when the differentiation could not be made by other imaging modalities

MeSH Terms

Abdomen/*radionuclide imaging
Chronic Disease
Diagnosis, Differential
Evaluation Studies
Female
Follow-Up Studies
Human
Male
Middle Age
Pancreatic Neoplasms/*radionuclide imaging
Pancreatitis/*radionuclide imaging
Prospective Studies
Reproducibility of Results
Sensitivity and Specificity
Support, Non-U.S. Gov't
Thallium Radioisotopes/*diagnostic use
Tomography, Emission-Computed, Single-Photon/methods