Korean J Nucl Med.  2000 Jun;34(3):222-227.

Left Ventricular Ejection Fraetion Determmed by Cated Tl-201 Perfusion SPECT and Quantitative Software

• Hyun IY
• Kim SE
• Seo JK
• Hong ES
• Kwan J
• Park KS
• Lee WH

Abstract

PURPOSE: We compared estimates of ejection fraction (EF) determined by gated Tl-201 perfusion SPECT (g-TI-SPECT) with those by gated blood pool (GBP) scan.
MATERIALS AND METHODS
Eighteen subjects underwent g-TI-SPECT and GBP scan. After reconstruction of g-TI-SPECT, we measured EF with Cedars software. The comparison of the EF with g-TI-SPECT and GHP scan was assessed by correlation analysis and Bland Altman plot.
RESULTS
The estimates of EF were significantly different (p<0.05) with g-TI-SPECT (40%+/-14%) and GBP scan (43%+/-14%). There was an excellent correlation of EF between e-TI-SPECT and GBP scan (r=0.94, p<0.001). The mean difference of EF between GRP scan and g-TI- SPECT was +3.2%, Ninety-five percent limits of agreement were +9,8%. EF between g-TI-SPECT and GBP scan were in poor agreement.
CONCLUSION
The estimates of EF by g-TI-SPECT was well correlated with those by GBP scan. However, EF of g-TI-SPECT doesn't agree with EF of GBP scan. EF of g-TI-SPECT cant be used interchangeably with EF of GBP scan.

Keyword

Left ventricular ejection fraction; TI-201; Gated myocardial perfusion SPECT

MeSH Terms

Perfusion*
Tomography, Emission-Computed, Single-Photon*