Pediatr Gastroenterol Hepatol Nutr.  2025 May;28(3):148-159. 10.5223/pghn.2025.28.3.148.

Dyslipidemia in Children and Adolescents: Current Insights and Updated Treatment Approaches

• Kim SE

• KMID: 2568306
• DOI: http://doi.org/10.5223/pghn.2025.28.3.148

Abstract

The increasing incidence of dyslipidemia among children and adolescents has emerged as a significant public health concern due to its associated risk of long-term cardiovascular complications. The prevalence of dyslipidemia has increased in parallel with rising obesity rates, highlighting the importance of early intervention. In this narrative review, we explore the epidemiology, screening, diagnosis, and treatment of dyslipidemia in pediatric populations, focusing on recent advancements and updates in clinical management. Key diagnostic criteria and risk assessment strategies are discussed, emphasizing the role of lipid profile screening in high-risk groups. Lifestyle and dietary interventions are key for managing dyslipidemia, while pharmacological treatments including statins, cholesterol absorption inhibitors, and emerging therapies are reviewed in cases requiring further intervention. Updated guidelines and evidence-based recommendations from Korean and other international institutions are consolidated to provide a comprehensive overview. These findings underscore the necessity of a multidisciplinary approach combining early detection, tailored treatment, and lifestyle modifications to mitigate the long-term health risks associated with dyslipidemia in younger individuals.

Keyword

Dyslipidemias, pediatrics; Epidemiology; Proprotein convertase 9