Korean J Blood Transfus.  2025 Apr;36(1):7-13. 10.17945/kjbt.2025.36.1.7.

Cross-Regional Supply of Washed Apheresis Platelets through Hospital-Blood Center Collaboration: A Case Experience

• Choi S
• Wee J
• Kim MU

• KMID: 2566833
• DOI: http://doi.org/10.17945/kjbt.2025.36.1.7

Abstract

A 64-year-old male patient diagnosed with B-cell lymphoma required regular platelet transfusions due to persistent thrombocytopenia. Over time, he developed severe transfusion-related allergic reactions, including anaphylaxis, necessitating the use of washed apheresis platelets (W-APLT). However, as the designated blood center was unable to produce W-APLT, the issue was resolved by collaborating with a neighboring blood center to source the product. Key strategies included verifying the patient’s history of transfusion-related anaphylaxis, coordinating the production schedule of blood products, and implementing administrative procedures such as pre-scheduled ambulance transport on the day of transfusion. These measures ensured the timely supply of W-APLT while minimizing the risk of product wastage. As a result, the patient successfully received multiple W-APLT transfusions without further allergic reactions. This case serves as a model for overcoming infrastructure limitations in W-APLT supply through hospital-blood center collaboration, to provide timely and safe blood products to patients at risk of severe transfusion-related allergic reactions and anaphylaxis.

Keyword

Washed platelet; Anaphylaxis; Blood bank; Transfusion reaction; Hospital-blood center collaboration