Arch Craniofac Surg.  2025 Feb;26(1):29-33. 10.7181/acfs.2024.00500.

An inflammatory myofibroblastic tumor of the soft tissue of the neck: a case report and literature review

Affiliations
  • 1Department of Surgery, Armed Forces Hospital Southern Region, College of Medicine, Bisha University, Khamis Mushait, Kingdom of Saudi Arabia
  • 2Department of Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt
  • 3Department of Pathology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia
  • 4Department of Surgery, College of Medicine, Bisha University, Khamis Mushait, Kingdom of Saudi Arabia

Abstract

Inflammatory myofibroblastic tumor (IMT) of the soft tissues of the neck is a rare pathological entity. We present the case of a 32-year-old patient who had a painful, slowly enlarging mass in the neck’s soft tissues. Radiological examination revealed a well-defined, dense lesion. The mass was surgically removed through local excision. Immunohistological analysis confirmed the diagnosis of IMT. After nearly 2 years of follow-up, there was no evidence of recurrence or distant metastases. In conclusion, although IMT of the soft tissues of the neck is uncommon, it should be considered in the differential diagnosis of neck tumors. Further research is necessary to understand the pathogenetic mechanisms of IMT, which could lead to the development of more effective treatments for this tumor.

Keyword

Anaplastic lymphoma kinase / Case reports / Inflammatory myofibroblastic tumor / Tropomyosin-3 / Tropomyosin-4 / World Health Organization
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