Ann Pediatr Endocrinol Metab.  2025 Feb;30(1):25-30. 10.6065/apem.2448072.036.

Impact of COVID-19 lockdown on blood glucose levels in pediatric patients with type 1 diabetes mellitus

• Cho MH
• Shim YS
• Lee HS

• KMID: 2565213
• DOI: http://doi.org/10.6065/apem.2448072.036

Abstract

Purpose
The coronavirus disease 2019 (COVID-19) pandemic brought stringent social distancing measures, resulting in changes to daily routines such as increased time at home, remote learning, altered meal schedules, and reduced physical activity. Therefore, we aimed to investigate the impact of the COVID-19 lockdown on glycemic control among pediatric patients with type 1 diabetes.
Methods
This study retrospectively analyzed the medical records of 47 pediatric patients with type 1 diabetes who visited Ajou University Hospital before and after the lockdown. To analyze the effects of the lockdown on glycemic control, we examined the change in glycated hemoglobin (HbA1c) levels before and after the lockdown.
Results
Among 47 patients, 23 (49%) were female and the average age before the lockdown as of March 2020 was 11.65±3.03 years. The mean HbA1c levels were 8.22%±1.69% and 7.86%±1.57% before and after the lockdown, respectively, showing better glycemic control during the lockdown (P=0.001). The decrease in HbA1c was more significant in subjects with higher pre-lockdown HbA1c levels, older patients, and individuals not using continuous glucose monitoring or continuous subcutaneous insulin infusion. However, from a long-term perspective, HbA1c levels at 3 years and 1 year before and after the lockdown were not significantly different.
Conclusion
This study demonstrated the beneficial effect of intensive social distancing for COVID-19 on blood glucose control in pediatric patients with type 1 diabetes mellitus. Furthermore, changes due to the lockdown had a more pronounced effect on patients with existing poor glycemic control.

Keyword

COVID-19; Type 1 diabetes; Glycemic control; Quarantine; Continuous glucose monitoring; Glycated hemoglobin; Body mass index

Figure

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  Fig. 1. HbA1c and BMI before lockdown (orange) and after lockdown (yellow). HbA1c, glycated hemoglobin; BMI, body mass index.

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  Fig. 2. Comparison of HbA1c averages 3 years and 1 year before (orange) and after (yellow) the COVID-19 lockdown period. HbA1c, glycated hemoglobin; COVID-19, coronavirus disease 2019.

Reference

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