J Gynecol Oncol.  2024 Jan;35(1):e9. 10.3802/jgo.2024.35.e9.

Comparison of survival outcomes between robotic and laparoscopic radical hysterectomies for early-stage cervical cancer: a systemic review and meta-analysis

• Hwang JH
• Kim B

• KMID: 2564870
• DOI: http://doi.org/10.3802/jgo.2024.35.e9

Abstract

Objective
Survival outcomes of robotic radical hysterectomy (RRH) remain controversial. Therefore, we performed a meta-analysis to evaluate survival outcomes between RRH) and laparoscopic radical hysterectomy (LRH) in patients with early-stage cervical cancer.
Methods
Studies comparing between RRH and LRH published up to November 2022 were systemically searched in the PubMed, Cochrane Library, Web of Science, ScienceDirect, and Google Scholar databases. Manual searches of related articles and relevant bibliographies of the published studies were also performed. Two researchers independently extracted data. Studies with information on recurrence and death after minimally invasive radical hysterectomy were also included. The extracted data were analyzed using the Stata MP software package version 17.0.
Results
Twenty eligible clinical trials were included in the meta-analysis. When all studies were pooled, the odds ratios of RRH for recurrence and death were 1.19 (95% confidence interval [CI]=0.91–1.55; p=0.613; I 2 =0.0%) and 0.96 (95% CI=0.65–1.42; p=0.558; I 2 =0.0%), respectively. In a subgroup analysis, the quality of study methodology, study size, country where the study was conducted, and publication year were not associated with survival outcomes between RRH and LRH.
Conclusion
This meta-analysis demonstrates that the survival outcomes are comparable between RRH and LRH.

Keyword

Uterine Cervical Neoplasm; Laparoscopy; Robotic Surgical Procedures; Hysterectomy; Survival Analysis