Med Lasers.
2024 Sep;13(3):142-149. 10.25289/ML.24.013.
Utilizing a high power light-emitting diode to induce apoptosis of uterine carcinosarcoma (malignant mixed mullerian tumor) cells through a bi-phasic effect
- Affiliations
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- 1Department of Obstetrics and Gynecology, Dankook University College of Medicine, Cheonan, Republic of Korea
- 2Department of Otorhinolaryngology-Head and Neck Surgery, Dankook University College of Medicine, Cheonan, Republic of Korea
- KMID: 2564462
- DOI: http://doi.org/10.25289/ML.24.013
Abstract
- Background
Malignant mixed mullerian tumor (MMMT), a carcinoma of the uterus, is a bi-phasic tumor composed of malignant epithelial and mesenchymal components. The treatment of MMMT remains a challenge despite advances in technology. This study is a preliminary investigation of the potential use of high power lightemitting diode (HPLED) modules as an alternative to laser therapy for cancer treatment.
Methods
This study used 656 and 850 nm HPLEDs at 50 mW power output within a non-thermal range duration. The viability and proliferation of the cells were analyzed after irradiation with the HPLEDs.
Results
A significant reduction in cancer cell viability was observed after irradiation with either the 656 or 850 nm HPLED.
Conclusion
This study shows the potential use of HPLEDs for cancer treatment.
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