Obstet Gynecol Sci.  2025 Jan;68(1):30-42. 10.5468/ogs.24226.

Decoding impact of human papillomavirus in gynecological oncology: a narrative review

Affiliations
  • 1Virology Laboratory, Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka, Bangladesh
  • 2Hospital, Nutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh

Abstract

Human papillomavirus (HPV) is a key factor in gynecological oncology. This narrative review investigates the complex connection between HPV and various gynecological cancers. For a comprehensive exploration, we examined the association between persistent HPV infection and cervical cancer and its global prevalence. Beyond the cervix, we navigated the linkages between HPV and other gynecological malignancies, shedding light on vulvar, vaginal, anal, and oropharyngeal cancers. The narrative extends to discuss the critical role of HPV vaccination in preventing these cancers and exploring challenges, controversies, and future perspectives in the field. As we have described the impact of HPV, this review underscores the significance of ongoing research and public health endeavors in shaping the trajectory of gynecological oncology.

Keyword

Human papillomavirus infections; Cervical cancer; Genital neoplasms
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