Nucl Med Mol Imaging.  2024 Dec;58(6):379-380. 10.1007/s13139-024-00864-3.

Unsuspected Isolated Peritoneal Metastasis of Prostate Cancer Detected with Digital F-18 PSMA PET/CT Scan

Affiliations
  • 1Department of Nuclear Medicine, PET/CT Unit, Gulf International Cancer Center, P.O. Box 5882, Abu Dhabi, UAE

Abstract

We report the case of a prostate cancer (PC) patient referred to our center to perform F-18 prostate-specific mem-brane antigen (PSMA) digital positron emission tomography / computed tomography (PET/CT) scan for biochemical recurrence. PET/CT was unremarkable except for a tiny PSMA-expressing nodule on the right paracolic gutter, which increased in size and PSMA-expression on repeat imaging. Excision of the lesion was consistent with PC peritoneal metastasis. The isolated location of the lesion was atypical for PC metastasis. In the era of highly sensitive digital PET/CT detectors, it is always important to investigate abnormal uptake of F-18 PSMA regardless of the location.

Keyword

Prostate cancer; PSMA; F-18; PET; Peritoneal metastasis
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