J Yeungnam Med Sci.
2025;42(1):5. 10.12701/jyms.2024.00766.
Pathology and diagnostic approaches to well-differentiated hepatocellular lesions: a narrative review
- Affiliations
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- 1Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea
- 2Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA
- KMID: 2563205
- DOI: http://doi.org/10.12701/jyms.2024.00766
Abstract
- Well-differentiated hepatocellular lesions (WDHLs) are liver tumors or nonneoplastic lesions in which the cells closely resemble normal hepatocytes. These lesions often include focal nodular hyperplasia, hepatocellular adenoma, macroregenerative nodule, dysplastic nodule, and well-differentiated hepatocellular carcinoma. The diagnosis of these lesions remains challenging because of their morphological similarities, particularly when examined using needle biopsy. The accurate diagnosis of WDHLs is crucial for patient management and prognosis. This review addresses the histopathological characteristics and diagnostic approaches of WDHLs.
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