J Mult Scler Neuroimmunol.  2023 Dec;14(2):110-113. 10.59578/jmsni.2023.14.2.110.

A Case of Post-Infective Myelin-Oligodendrocyte Glycoprotein Antibody-Associated Disease

Affiliations
  • 1Department of Neurology, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, Korea
  • 2Department of Neurology, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea

Abstract

Anti-myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G (IgG)-associated disease (MOGAD) is an immune-mediated central nervous system inflammatory demyelinating disorder that has been widely recognized in recent years. Herein, we describe the case of a 27-year-old woman with MOGAD following an upper respiratory infection. The patient was hospitalized for quadriparesis and drowsiness. Brain and spine MRI revealed abnormalities in multiple sites. She was initially considered to have infectious encephalomyelitis or acute disseminated encephalomyelitis (ADEM). This case report of a young woman who presented with ADEM that led to a MOGAD diagnosis after upper respiratory infection can potentially aid in elucidating the pathophysiology of this disease.

Keyword

Myelin oligodendrocyte glycoprotein; Myelin-oligodendrocyte glycoprotein antibody-associated disease; Neuromyelitis optica; Encephalomyelitis
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