Ann Liver Transplant.  2024 Nov;4(2):129-133. 10.52604/alt.24.0018.

Two cases of living donor liver transplantation for colorectal liver metastases in Korea

• Alshamrani A
• Lee E
• Rhu Y
• An S
• Jo S
• Oh N
• Rhu J
• Kim J

• KMID: 2561860
• DOI: http://doi.org/10.52604/alt.24.0018

Abstract

Colorectal cancer (CRC) poses a significant global health challenge, particularly with patients often experiencing liver metastases. Surgical resection remains the standard treatment; however, many patients face ineligibility due to disease status, contributing to poor prognoses. Liver transplantation (LT) is a viable alternative for select patients with advanced disease. This case report details the clinical outcomes of two CRC patients with multiple liver metastases who successfully underwent living donor LT (LDLT). Both individuals had intricate medical histories and pre-existing liver issues. Patient 1, a 58-year-old male, received extensive pre-transplant interventions, including multiple radiofrequency ablations and pulmonary resections. Patient 2, a 50-year-old male, had cirrhosis alongside colorectal cancer with liver metastases and completed chemotherapy. The cases illustrate LDLT's viability and potential advantages for complex CRC cases with liver metastases. The patients’ intricate medical backgrounds necessitate thorough pre-transplant evaluations and vigilant post-transplant supervision. Moreover, these cases highlight the critical nature of ongoing follow-up for evaluating long-term survival and recognizing possible complications.

Keyword

Patient selection; Donor selection; Living donors; Colon cancer; Rectal cancer