J Cosmet Med.  2018 Dec;2(2):85-90. 10.25056/JCM.2018.2.2.85.

Association between metabolic syndrome and blepharoptosis in the Korean adults: the Korea National Health and Nutrition Examination Survey 2010–2012

• Koh C
• Kim G
• Han K
• Park J

• KMID: 2561058
• DOI: http://doi.org/10.25056/JCM.2018.2.2.85

Abstract

Background
Metabolic syndrome (MetS) is a complex disorder featuring chronic inflammation characterized by abdominal obesity, hyperglycemia, hypertension, and dyslipidemia. Recent studies have documented that MetS is associated with various diseases, including ocular disorders.
Objective
This cross-sectional study is based on data from the fifth Korea National Health and Nutrition Examination Surveys. We examined the association between MetS and its components with blepharoptosis in Korean adults aged 19 years or older.
Methods
MetS was defined using the criteria proposed by the American Heart Association and the National Heart, Lung, and Blood Institute together with the International Diabetes Federation in 2009. Blepharoptosis was defined as the marginal reflex distance 1 of <2 mm.
Results
The prevalence of blepharoptosis was 11.5%. As the number of MetS components increased, the prevalence of blepharoptosis also increased. After being controlled for various confounders, MetS was significantly associated with blepharoptosis (adjusted odds ratio [OR], 1.316; 95% confidence interval [CI], 1.133-1.529). In addition, blepharoptosis was associated with increased waist circumference, hypertension, and elevated triglyceride (adjusted OR, 95% CI; 1.281 [1.047-1.567], 1.165 [1.014-1.339], and 1.174 [1.013-1.36], respectively).
Conclusion
Consequently, MetS and its components were associated with blepharoptosis in Korean adults. Screening for blepharoptosis is warranted for patients with MetS.

Keyword

blepharoptosis; metabolic syndome