Ann Clin Neurophysiol.  2024;26(2):63-66. 10.14253/acn.24004.

Hypersomnia secondary to severe acute respiratory syndrome coronavirus-2 infection

• Quelle NB

• KMID: 2560434
• DOI: http://doi.org/10.14253/acn.24004

Abstract

Excessive daytime sleepiness (EDS), with or without an excessive need for sleep, is a primary reason for patients seeking consultation at the sleep unit. EDS is observed in ~5% of the general population. Common causes of EDS include obstructive sleep apnea, sleep deprivation, effects of medication, psychiatric disease (especially depression), and circadian rhythm disorders. Coronavirus disease 2019 (COVID-19) infection is a rare cause of EDS. We present a case of mild COVID-19 infection as an unusual cause of hypersomnolence.

Keyword

Hypersomnolence; Hypersomnolence; COVID-19; COVID-19

Reference

1. Bassetti C, McNicholas W, Paunio T, Peigneux P. Sleep medicine textbook. 2nd ed. Bonn: European Sleep Research Society;2022. p. 379–411.

2. Moura AEF, Oliveira DN, Torres DM, Tavares-Júnior JWL, Nóbrega PR, Braga-Neto P, et al. Central hypersomnia and chronic insomnia: expanding the spectrum of sleep disorders in long COVID syndrome - a prospective cohort study. BMC Neurol. 2022; 22:417.

3. Davis HE, Assaf GS, McCorkell L, Wei H, Low RJ, Re’em Y, et al. Characterizing long COVID in an international cohort: 7 months of symptoms and their impact. EclinicalMedicine. 2021; 38:101019.

4. Davis HE, McCorkell L, Vogel JM, Topol EJ. Long COVID: major findings, mechanisms and recommendations. Nat Rev Microbiol. 2023; 21:133–146.

5. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, et al. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Sci Rep. 2021; 11:16144.

6. Soriano JB, Murthy S, Marshall JC, Relan P, Diaz JV. A clinical case definition of post-COVID-19 condition by a Delphi consensus. Lancet Infect Dis. 2022; 22:e102–e107.

7. Merikanto I, Dauvilliers Y, Chung F, Wing YK, De Gennaro L, Holzinger B, et al. Sleep symptoms are essential features of long-COVID - comparing healthy controls with COVID-19 cases of different severity in the international COVID sleep study (ICOSS-II). J Sleep Res. 2023; 32:e13754.

8. Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, et al. Post-acute COVID-19 syndrome. Nat Med. 2021; 27:601–615.

9. Yong SJ. Persistent brainstem dysfunction in long-COVID: a hypothesis. ACS Chem Neurosci. 2021; 12:573–580.

10. Xu Y, Zhuang Y, Kang L. A review of neurological involvement in patients with SARS-CoV-2 infection. Med Sci Monit. 2021; 27:e932962.