Child Health Nurs Res.  2024 Oct;30(4):245-254. 10.4094/chnr.2024.004.

Effectiveness of cryotherapy in preventing oral mucositis in pediatric cancer patients in Jordan: a randomized controlled trial

• Banat K
• Al-Haja H
• Ananbeh M
• Abdullah E
• Alloubani A

• KMID: 2560340
• DOI: http://doi.org/10.4094/chnr.2024.004

Abstract

Purpose
The study aimed to evaluate the effectiveness of cryotherapy in preventing oral mucositis in pediatric patients receiving chemotherapy.
Methods
An evidence-based practice project utilized a randomized control trial design with two groups (experimental and control groups). Fifty-nine pediatric patients with cancer in Jordan, aged 8–18 years, were randomly assigned to the experimental group (n=29) or the control group (n=30). The intervention was conducted from June 2022 to December 2022. The severity of oral mucositis among pediatric cancer patients was assessed using the World Health Organization oral mucositis grade.
Results
There were no significant differences in sex or disease type among the groups. On days 7, 14, and 21, we observed notable between-group differences in treatment responses and the intensity of oral mucositis, highlighting the efficacy of cryotherapy in diminishing the severity of oral mucositis.
Conclusion
This study supports the use of cryotherapy as a preventive measure for oral mucositis among pediatric oncology patients in Jordan. The findings suggest that cryotherapy effectively reduces the severity of oral mucositis. Further research is necessary to investigate the broader impacts of cryotherapy.

Keyword

Cryotherapy; Neoplasms; Pediatrics; Prevention and control; Stomatitis