Korean J Fam Pract.  2024 Sep;14(3):133-142. 10.21215/kjfp.2024.14.3.133.

Risk of Depression Associated with Common Chronic Eye Diseases: A Study Using the 8th Korea National Health and Nutrition Examination Survey (2019–2021)

• Park J
• Noh M

• KMID: 2559905
• DOI: http://doi.org/10.21215/kjfp.2024.14.3.133

Abstract

Background
Chronic diseases increase the risk of depression. We selected the most frequent chronic eye diseases and their combinations. We compared the risk of diagnosis and the current prevalence of depression based on eye diseases and their combinations.
Methods
Data from the 8th Korea National Health and Nutrition Examination Survey (2019–2021), which included responses from 10,910 adults aged 18 years or older who answered a questionnaire on eye diseases and diagnosis of depression, were analyzed. The study group and control group consists of 3,007 and 7,903 individuals. In the study group, individuals with a single eye disease were categorized as having cataracts, dry eye, glaucoma, macular degeneration, or other eye diseases. Patients with two eye diseases were categorized as having glaucoma with cataracts, cataracts with dry eye, cataracts with macular degeneration, or two other eye diseases. The remaining patients were classified as having three or more eye diseases. Chi-square tests and multiple logistic regression analysis using correction variables were used for statistical analysis.
Results
The high-risk factors for depression in the past were cataracts with macular degeneration, cataracts with dry eyes, glaucoma, cataracts, and dry eye. The risk of current depression was statistically significant only for cataracts with macular degeneration, cataracts with dry eye, cataracts, and dry eye.
Conclusion
Patients with eye diseases that are highly associated with depression require active screening and treatment.

Keyword

Depression; Eye Diseases; KNHANES; Korea