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Bioactive Lipids and Their Derivatives in Biomedical Applications

Park J, Choi J, Kim DD, Lee S, Lee B, Lee Y, Kim S, Kwon S, Noh M, Lee MO, Le QV, Oh YK

Lipids, which along with carbohydrates and proteins are among the most important nutrients for the living organism, have a variety of biological functions that can be applied widely in biomedicine....
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Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders

Han YH, Lee K, Saha A, Han J, Choi H, Noh M, Lee YH, Lee MO

Uncontrolled inflammation is considered the pathophysiological basis of many prevalent metabolic disorders, such as nonalcoholic fatty liver disease, diabetes, obesity, and neurodegenerative diseases. The inflammatory response is a self-limiting process...
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Relationship of computed tomography and emergency department revisits in febrile elderly patients

Noh M, Cho J, Beom J, Han E

  • KMID: 2519737
  • J Korean Soc Emerg Med.
  • 2021 Aug;32(4):328-336.
Objective: The number of elderly people visiting emergency rooms is rapidly increasing. Fever is one of the common complaints of patients who come to the emergency room, and it is...
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Association between Laterality and Location of Deep Vein Thrombosis of Lower Extremity and Pulmonary Embolism

Gong S, Lee EJ, Kim JS, Kim H, Noh M, Park H, Park BW, Yang S, Park SJ

Purpose: The aim of this study was to investigate the relationship between the anatomical location of thrombi in the lower extremities and the development of pulmonary embolism (PE). Materials and Methods:...
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Advanced Stage Hepatocellular Carcinoma Successfully Treated with Liver-directed Concurrent Chemoradiotherapy and Sequential Transarterial Radio-embolization

Noh M, Kim BK, Kim SU

Optimal treatment strategies for patients with advanced hepatocellular carcinoma (HCC) is yet to be determined. Herein, we present a case of advanced HCC with tumor invasion into the right anterior...
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Diallyl Biphenyl-Type Neolignans Have a Pharmacophore of PPARα/γ Dual Modulators

Han Y, Liu J, Ahn S, An S, Ko H, Shin JC, Jin SH, Ki MW, Lee SH, Lee KH, Shin SS, Choi WJ, Noh M

Adiponectin secretion-promoting compounds have therapeutic potentials in human metabolic diseases. Diallyl biphenyl-type neolignan compounds, magnolol, honokiol, and 4-O-methylhonokiol, from a Magnolia officinalis extract were screened as adiponectin-secretion promoting compounds in...
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LJ-2698, an Adenosine A3 Receptor Antagonist, Alleviates Elastase-Induced Pulmonary Emphysema in Mice

Boo HJ, Park SJ, Noh M, Min HY, Jeong LS, Lee HY

Emphysema, a major component of chronic obstructive pulmonary disease (COPD), is a leading cause of human death worldwide. The progressive deterioration of lung function that occurs in the disease is...
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IL-1 Receptor Antagonist Reduced Chemical-Induced Keratinocyte Apoptosis through Antagonism to IL-1α/IL-1β

Lee H, Cheong KA, Kim JY, Kim NH, Noh M, Lee AY

Extracellular interleukin 1 alpha (IL-1α) released from keratinocytes is one of the endpoints for in vitro assessments of skin irritancy. Although cells dying via primary skin irritation undergo apoptosis as...
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Establishment of Immortalized Primary Human Foreskin Keratinocytes and Their Application to Toxicity Assessment and Three Dimensional Skin Culture Construction

Choi M, Park M, Lee S, Lee JW, Cho MC, Noh M, Lee C

In spite of frequent usage of primary human foreskin keratinocytes (HFKs) in the study of skin biology, senescence-induced blockage of in vitro proliferation has been a big hurdle for their...
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Septic Arthritis Caused by Bacteroides thetaiotaomicron Bacteremia in a Patient with Multiple Myeloma

Noh M, Kim B, Kim J, Choi H, Yeom J, Jung T, Pai H

Septic arthritis is rarely caused by anaerobic bacteria, which is mostly secondary to hematogenous dissemination among the immunocompromised host. We report a patient of septic arthritis on the right knee...
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Analysis of Risk Factors for Cerebral Microinfarcts after Carotid Endarterectomy and the Relevance of Delayed Cerebral Infarction

Gwon JG, Kwon TW, Cho YP, Kang DW, Han Y, Noh M

BACKGROUND AND PURPOSE: Carotid endarterectomy (CEA) is performed to prevent cerebral infarction, but a common side effect is cerebral microinfarcts. This study aimed to identify the variables related to the...
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Volumetric Changes in the Bony External Auditory Canal in Unilateral Chronic Otitis Media

Park JH, Noh M, Lee CK, Park SB, Park KH, Han JK, Kim HJ

BACKGROUND AND OBJECTIVES: Pneumatization of air cells in the mastoid bone is decreased in chronic otitis media (COM). A decrease in the size of the external auditory canal (EAC) is...
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miR-526b targets 3' UTR of MMP1 mRNA

Kim KH, Jung JY, Son ED, Shin DW, Noh M, Lee TR

Regulation of matrix metalloproteinases (MMPs) is important for many physiological processes involving cancers, inflammation, tissue remodeling and skin aging. Here, we report the novel finding that the expression of MMP1...
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A Cannabinoid Receptor Agonist N-Arachidonoyl Dopamine Inhibits Adipocyte Differentiation in Human Mesenchymal Stem Cells

Ahn S, Yi S, Seo WJ, Lee MJ, Song YK, Baek SY, Yu J, Hong SH, Lee J, Shin DW, Jeong LS, Noh M

Endocannabinoids can affect multiple cellular targets, such as cannabinoid (CB) receptors, transient receptor potential cation channel, subfamily V, member 1 (TRPV1) and peroxisome proliferator-activated receptor gamma (PPARgamma). The stimuli to...
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Clinical outcomes of staged bilateral carotid endarterectomy for bilateral carotid artery stenosis

Kim A, Kwon TW, Han Y, Kwon SU, Kwon H, Noh M, Cho YP

PURPOSE: This retrospective cohort study aimed to determine the clinical outcomes of staged bilateral carotid endarterectomy (CEA) for bilateral internal carotid artery (ICA) stenosis performed with a short interval between...
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Keratinocytic Vascular Endothelial Growth Factor as a Novel Biomarker for Pathological Skin Condition

Bae ON, Noh M, Chun YJ, Jeong TC

Skin is an emerging target tissue in pharmaceutical and cosmetic science. Safety assessment for dermal toxicity is a critical step for development of topically applicable pharmaceutical agents and ingredients in...
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The Effect of Acute Coagulopathy in Profoundly Traumatic Patients on Acute and Early Deaths

Noh M, Yang SS, Kyoung KH

PURPOSE: Numerous studies have investigated the pattern of traumatic death with a focus on the injury mechanism, the severity of the injury and the presence of hemorrhage. Acute coagulopathy has...
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Three New Single Nucleotide Polymorphisms Identified by a Genome-Wide Association Study in Korean Patients with Vitiligo

Cheong KA, Kim NH, Noh M, Lee AY

Genetic susceptibility is involved in the pathogenesis of vitiligo. Association studies with a whole genome-based approach instead of a single or a few candidate genes may be useful for discovering...
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Are There Spatial and Temporal Correlations in the Incidence Distribution of Scrub Typhus in Korea?

Noh M, Lee Y, Chu C, Gwack J, Youn SK, Huh S

Objectives: A hierarchical generalized linear model (HGLM) was applied to estimate the transmission pattern of scrub typhus from 2001 to 2011 in the Republic of Korea, based on spatial and temporal...
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Spatial and Temporal Distribution of Plasmodium vivax Malaria in Korea Estimated with a Hierarchical Generalized Linear Model

Noh M, Lee Y, Oh S, Chu C, Gwack J, Youn SK, Cho SH, Lee WJ, Huh S

Objectives The spatial and temporal correlations were estimated to determine Plasmodium vivax malarial transmission pattern in Korea from 2001–2011 with the hierarchical generalized linear model. Methods Malaria cases reported to the Korea Centers...
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