Infect Chemother.
2024 Sep;56(3):361-368. 10.3947/ic.2024.0056.
Opportunistic Infections in HIV-Infected Children on Treatment in Southern Morocco: A 12-Years Retrospective Follow-up Study
- Iziki H
1,2 - Yakini S2,3
- Ouabich R4
- Bounabe A1,5
- Doukkani N1
- Ben-Abjaou N1
- Taleb SB1
- Blaak H1,6
- Boutib A7
- Barkat A2
- Affiliations
-
- 1Higher Institute of Nursing Professions and Health Techniques of Agadir, Agadir, Morocco
- 2Laboratory of Mother-Child Health and Nutrition Research, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University of Rabat, Rabat, Morocco
- 3Higher Institute of Nursing Professions and Health Techniques of Marrakech, Marrakech, Morocco
- 4LDPU, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech, Morocco
- 5LIGEP, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco
- 6Faculty of Medicine and Pharmacy of Rabat, Mohammed V University of Rabat, Rabat, Morocco
- 7Laboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, Settat, Morocco
- KMID: 2559766
- DOI: http://doi.org/10.3947/ic.2024.0056
Abstract
- Background
Human immunodeficiency virus (HIV) infection in children is a significant public health concern, increasing the risk of infant mortality. Immunodeficiency caused by HIV favors the development of opportunistic infections (OIs), which are responsible for over 90% of HIV-related deaths. This study seeks to determine the primary OIs in children with HIV followed at the Hassan II Regional Hospital Center in Sous Massa, during the period from 2012 to 2023.
Materials and Methods
This retrospective study is the first in Morocco to investigate OIs among HIV-infected children. It analyzed 76 complete medical records, using a data collection form designed based on existing literature.
Results
This study revealed that 37% of participants were suffering from OIs, mainly diarrhea (11%), tuberculosis (9%) and pneumonia (7%).There was a significant correlation between OIs and HIV clinical stage (P=0.001), age (P=0.007), and anemia (P=0.001). Despite progress in management, the presence of OIs remains a risk factor for infant morbidity and mortality.
Conclusion
The study highlights the importance of early detection, prevention, and adherence to treatment in reducing this burden. Management of anemia is essential.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Clinical Guidelines for the Treatment and Prevention of Opportunistic Infections in HIV-infected Koreans
- The 2015 Clinical Guidelines for the Treatment and Prevention of Opportunistic Infections in HIV-Infected Koreans: Guidelines for Opportunistic Infections
- Common Infectious Diseases in HIV Infected Persons
- Treatment and Prevention of Opportunistic Infections in HIV-Infected Patients
- Clinical Features of Opportunistic Diseases of Neck in HIV-Infected Patients
