Korean J Blood Transfus.
2024 Aug;35(2):135-136. 10.17945/kjbt.2024.35.2.135.
Reappraisal of ABO-Blood Group Testing for Neonates: Can We Omit Back Typing?
- Affiliations
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- 1Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- 2Department of Laboratory Medicine, Chungbuk National University Hospital, Cheongju, Korea
- 3Department of Laboratory Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea
- 4Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea
- KMID: 2558987
- DOI: http://doi.org/10.17945/kjbt.2024.35.2.135
Abstract
- ABO-blood typing typically involves both front typing (cell typing) and back typing (serum typing) to ensure accurate determination of blood type. However, in neonates, back typing is frequently omitted due to their immature immune system. If an institution chooses red blood cells (RBCs) that match the neonate's blood type, omitting back typing could lead to unexplained cross-matching incompatibilities. Therefore, blood banks should be cautious with neonatal blood typing and transfusion practices to ensure transfusion safety.
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