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Impact of Familial Pseudohyperkalemia on Donated Blood and Clinical Outcomes from Transfusion

Chung Y, Kim HJ, Kim H, Ko DH

Familial pseudohyperkalemia (FP) is a dominantly inherited condition caused by variants in the gene ABCB6 resulting in red blood cell (RBC) membrane protein defects. FP is generally asymptomatic. However, FP...
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Assessing the impact of recombination on the estimation of isolation-with-migration models using genomic data: a simulation study

Chung Y

Recombination events complicate the evolutionary history of populations and species and have a significant impact on the inference of isolation-with-migration (IM) models. However, several existing methods have been developed, assuming...
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Efficacy of Acetylcysteine and Selenium in Aneurysmal Subarachnoid Hemorrhage Patients: A Prospective, Multicenter, Single Blind Randomized Controlled Trial

Kim M, Jeon H, Chung Y, Lee SU, Park W, Park JC, Ahn JS, Lee S

Background: Subarachnoid hemorrhage (SAH) patients have oxidative stress results in inflammation, tissue degeneration and neuronal damage. These deleterious effects cause aggravation of the perihematomal edema (PHE), vasospasm, and even hydrocephalus....
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Is Leukoreduction Needed for Plasma Products?

Youk HJ, Chung Y, Kim H, Ko DH

Leukoreduction is a process in which the white blood cells (WBCs) in cellular products are intentionally reduced to bring down the risk of adverse transfusion reactions, such as febrile nonhemolytic...
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Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019 in Korea

Chung Y, Kim EJ, Kim HS, Park KH, Baek JH, Kim J, Lee JY, Lee CS, Lim S, Kim SW, Kim ES, Shi HJ, Hong SH, Jun JB, Hong KW, Choi JP, Kim J, Yang KS, Yoon YK

Background: This study aimed to describe the maternal, obstetrical, and neonatal outcomes in pregnant women with coronavirus disease 2019 (COVID-19) and identify the predictors associated with the severity of COVID-19. Methods:...
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The effect of missing levels of nesting in multilevel analysis

Park S, Chung Y

Multilevel analysis is an appropriate and powerful tool for analyzing hierarchical structure data widely applied from public health to genomic data. In practice, however, we may lose the information on...
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Transfusion of the Least-incompatible Blood with Intravenous Immunoglobulin and Steroid to a Patient with Anti-Fya

Yu J, Kim JS, Yang JJ, Chung Y, Kim H, Hwang SH, Oh HB, Youk HJ, Ko DH

Antibody to high-incidence antigens is one of the most challenging issues in transfusion medicine. Transfusion of the least-incompatible red blood cell (RBC) unit is standard practice, which may sometimes result...
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Laboratory support of ABO antibody monitoring for ABO-incompatible solid organ transplantation

Chung Y, Ko DH

The accurate measurement of ABO antibodies is essential for successful ABO-incom-patible solid organ transplantation. Titration using two-fold dilution is considered a standard method and is applied in most laboratories. However,...
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A Pilot Project for the Expansion of the External Quality Assessment Program in Transfusion Medicine: Anti-D Titer Test

Chung Y, Kim JS, Youk HJ, Hwang SH, Oh HB, Kim H, Ko DH

Background: Many test items in transfusion medicine that are still not included in the Korean Association of External Quality Assessment Service. We performed a pilot project of anti-D titer test for...
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Application of Geometric Mean Criteria for AntiBlood Group Antibody Proficiency Testing in the Korean External Quality Assurance Program

Yang JJ, Youk HJ, Chung Y, Kim H, Hwang SH, Oh HB, Ko DH

Background: The geometric mean criteria (GC) is an alternative for assessing proficiency testing (PT) acceptability. A recent study applied GC to the PT results provided by the College of American...
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Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma

Lee Y, Lee J, Kim H, Park C, Jung J, Kim D, Chung Y, Ryu H

Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted...
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Golden Age of Immunotherapy: Challenges and Opportunities

Chung Y, Lee SW, Kim WU

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Trochlear Nerve Palsy Caused by a Superior Cerebellar Artery Aneurysm

Park JW, Han HJ, Chung Y, Han SY

Purpose: We report a case of trochlear nerve palsy caused by a superior cerebellar artery (SCA) aneurysm. Case summary: A 34-year-old woman visited our clinic complaining of distance diplopia and a...
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The Impact of National Health Insurance Coverage on Compliance With Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea

Choi W, Bae M, Chung Y

Objectives. Compliance with positive airway pressure (PAP) in patients with obstructive sleep apnea (OSA) directly affects its treatment efficacy. Since July 2018, polysomnography and PAP therapy have been covered by...
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Coincidental Nasopharyngeal Carcinoma and Ventral Foramen Magnum Meningioma: Case Report and Review of the Literature

Bae Y, Oh W, Chung Y, Won YS, Hong JB

Multiple primary tumors at adjacent site are rare. We report a rare case of coincidentally found nasopharyngeal cancer and ventral foramen magnum meningioma. The 68-year-old male patient presented with a...
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The influence of the dietary intake of vitamin C and vitamin E on the risk of gastric intestinal metaplasia in a cohort of Koreans

Park SK, Chung Y, Oh CM, Ryoo JH, Jung JY

OBJECTIVES: Studies have suggested that the dietary intake of antioxidant vitamins, such as vitamin C and vitamin E, has a potential role in inhibiting gastric carcinogenesis. The present study investigated...
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Current Status of Management for Transfusion Management Division at Ten Medical Institutions in Korea

Youk HJ, Chung Y, Kim H, Hwang SH, Oh HB, Ko DH

Background: According to the revision of the Blood Management Act in 2020, medical institutions that meet certain conditions are obliged to install a transfusion management division in Korea. Therefore, this...
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Safety of Red Blood Cell Transfusion by the Emergency Blood Transfusion Protocol

Jung K, Lee J, Kang JS, Park JH, Chung Y, Ko DH, Kim H, Han KS

Background: Pretransfusion testing is vital for safe transfusion. However, in situations without time to perform sufficient testing, all or part of the pretransfusion testing may be skipped to issue blood...
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Current Status of External Quality Control for the Classification of Complex Antibodies on the Unexpected Antibody Identification Test

Youk HJ, Kim JS, Chung Y, Hwang SH, Oh HB, Kim H, Ko DH

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Endoscopic Management of Staple Line Leak after Bariatric Surgery: Surgeon’s Perspective

Chung Y, Park DG, Kim YJ

Laparoscopic sleeve gastrectomy (LSG) has become a standalone primary procedure as a bariatric metabolic surgery since the early 2000s. The overall complication rate of LSG is reported to range from...
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