Korean J Intern Med.
2024 Sep;39(5):845-854. 10.3904/kjim.2023.476.
High vegetable consumption and regular exercise are associated with better quality of life in patients with gout
- Do H1
- Choi HJ2
- Choi B3
- Son CN4
- Kim SH5
- Ha YJ6
- Kim JH7
- Kim MJ8
- Shin K8
- Kim HO9
- Song R10
- Lee SW11
- Ahn JK12
- Lee SG13
- Lee CH14
- Son KM15
- Moon KW
1
- Affiliations
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- 1Division of Rheumatology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea
- 2Division of Rheumatology, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea
- 3Division of Rheumatology, Department of Internal Medicine, Seoul Medical Center, Seoul, Korea
- 4Division of Rheumatology, Department of Internal Medicine, Eulji University School of Medicine, Uijeongbu, Korea
- 5Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
- 6Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
- 7Division of Rheumatology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea
- 8Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea
- 9Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea
- 10Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, Korea
- 11Division of Rheumatology, Department of Internal Medicine, Soon Chun Hyang University Hospital, Cheonan, Korea
- 12Division of Rheumatology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
- 13Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Korea
- 14Division of Rheumatology, Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea
- 15Division of Rheumatology, Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea
- KMID: 2558775
- DOI: http://doi.org/10.3904/kjim.2023.476
Abstract
- Background/Aims
The Gout Impact Scale (GIS), a part of the Gout Assessment Questionnaire 2.0, is used to measure gout-specific health-related quality of life (HRQOL). Although several studies have been conducted on the factors affecting the HRQOL of patients with gout, few have focused on lifestyle factors. This study aimed to investigate the correlation between lifestyle habits and HRQOL using the GIS in patients with gout.
Methods
We used data from the Urate-Lowering TheRApy in Gout (ULTRA) registry, a prospective cohort of Korean patients with gout treated at multiple centers nationwide. The patients were aged ≥18 years and met the 2015 American College of Rheumatology/European League Against Rheumatism gout classification criteria. They were asked to complete a GIS and questions regarding their lifestyle habits at enrollment.
Results
The study included 232 patients. ‘Gout concern overall’ scores in the GIS were significantly lower in patients who exercised more frequently and consumed soft drinks and meat less, and ‘well-being during attack’ scores were significantly lower in patients who consumed vegetables and exercised more frequently. The frequency of vegetable consumption had a negative linear relationship with the ‘well-being during attack’ and ‘gout concern during attack’ scores (p = 0.01, p = 0.001, respectively). The frequency of exercise had a negative linear relationship with the ‘gout concern overall’ and ‘gout concern during attack’ scores (p = 0.04 and p = 0.002, respectively).
Conclusions
Patients with gout who frequently consumed vegetables and exercised regularly experienced less impact of gout, exhibiting a better GIS that represented HRQOL.
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