Ann Coloproctol.  2024 May;40(Suppl 1):S23-S26. 10.3393/ac.2022.00444.0063.

Melanocytic nevus of the anal canal and granular cell tumor of the cecum: a case report and literature review of 2 coincidentally co-occurring neurocristopathies

• Sandoval V
• Lara-Endara J
• Rodríguez-Suárez J
• Garzón WA
• Redrobán L
• Montalvo N

• KMID: 2556092
• DOI: http://doi.org/10.3393/ac.2022.00444.0063

Abstract

Granular cell tumors are predominantly benign soft tissue tumors originating from Schwann cells, whereas melanocytic nevi are benign proliferations of melanocytes. We present the case of a patient with the presence of both entities located in the cecum and anal canal, respectively, constituting an extremely rare coincidental finding. A 43-year-old woman was evaluated by colonoscopy for iron-deficiency microcytic anemia that had lasted for 1 year. Colonoscopy demonstrated a macular lesion of 0.3 cm with a melanocytic appearance in the anal canal; at the cecum level, a subepithelial, yellowish, and partially mobile firm nodular lesion measuring 1.3 cm was observed. A histopathological study showed a melanocytic nevus in the anal canal and a granular cell tumor in the cecum. This is the first reported case of a patient with the extremely rare coincidental-incidental finding of these 2 entities at the same time.

Keyword

Cecum; Granular cell tumor; Anal; Melanocytic nevus; Neurocristopathies; Case report