Clin Endosc.  2024 May;57(3):415-416. 10.5946/ce.2024.007.

A rare colonoscopic finding in a renal transplant recipient

Affiliations
  • 1Department of Health Promotion Medicine, Ewha Womans University Seoul Hospital, Seoul, Korea
  • 2Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
  • 3Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 4Inflammatory Bowel Disease Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea


Figure

  • Fig. 1. Colonoscopy with the use of (A, B) white light and (C, D) narrow-band imaging reveals multiple whitish flat or slightly elevated mucosal lesions measured 10 to 20 mm in diameter at the ascending colon.

  • Fig. 2. Histopathologic findings. (A) The lesions consist predominantly of histiocytes with eosinophilic granular cytoplasm (von Hansemann cells) (arrows) (hematoxylin and eosin stain, ×200). (B) The lesions are positive for CD68 (PG-M1, ×400).

  • Fig. 3. (A, B) Colonoscopy following after 6 months of antibiotics treatment shows complete resolution of all lesions.


Reference

1. Mitchell A, Dugas A. Malakoplakia of the colon following renal transplantation in a 73 year old woman: report of a case presenting as intestinal perforation. Diagn Pathol. 2019; 14:22.
2. Ajabnoor R, Mawardi M, Almutawa A. Colonic malakoplakia in a liver transplant recipient: a case report. Hum Pathol Case Rep. 2019; 18:200323.
3. Hyun KH, Shin HD, Kim DH. Malakoplakia in a healthy young female patient. Korean J Intern Med. 2013; 28:475–480.
4. Mousa OY, Corral JE, Nassar A, et al. Colonic mass and chronic diarrhea in a renal transplant patient: an uncommon case of malakoplakia: 1441. Am J Gastroenterol. 2017; 112:S783. S785.
5. Haq K. Malakoplakia in kidney transplant recipients. Kidney News. 2023; 15:10.
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