Gut Liver.  2024 May;18(3):404-413. 10.5009/gnl230093.

Progress and Clinical Applications of Crohn’s Disease Exclusion Diet in Crohn’s Disease

Affiliations
  • 1Departments of Gastroenterology, Xiangya Hospital of Central South University, Changsha, China
  • 2Departments ofClinical Nutrition, Xiangya Hospital of Central South University, Changsha, China
  • 3Hunan Key Laboratory of Organ Fibrosis, Changsha, China
  • 4Hunan International Scientific and Technological Cooperation Base of Artificial Intelligence Computer Aided Diagnosis and Treatment for Digestive Disease, Changsha, China
  • 5National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

Abstract

Crohn’s disease is a chronic intestinal inflammatory disorder of unknown etiology. Although the pharmacotherapies for Crohn’s disease are constantly updating, nutritional support and adjuvant therapies have recently gained more attention. Due to advancements in clinical nutrition, various clinical nutritional therapies are used to treat Crohn’s disease. Doctors treating inflammatory bowel disease can now offer several diets with more flexibility than ever. The Crohn’s disease exclusion diet is a widely used diet for patients with active Crohn’s disease. The Crohn’s disease exclusion diet requires both exclusion and inclusion. Periodic exclusion of harmful foods and inclusion of wholesome foods gradually improves a patient’s nutritional status. This article reviews the Crohn’s disease exclusion diet, including its structure, mechanisms, research findings, and clinical applications.

Keyword

Crohn disease; Nutritional therapy; Crohn’s disease exclusion diet; Clinical applications
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