Korean J Vet Res.  2024 Mar;64(1):e8. 10.14405/kjvr.20240011.

Penile neoplasm associated with Equus caballus papillomavirus type 2 infection in a miniature Appaloosa: a case report

Affiliations
  • 1Veterinary Center, Korea Racing Authority, Gwacheon 13822, Korea
  • 2Equine Clinic, Jeju Stud Farm, Korea Racing Authority, Jeju 63346, Korea
  • 3Equine Hospital, Jeju Racecourse Park, Korea Racing Authority, Jeju 63066, Korea
  • 4Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea

Abstract

An 18-year-old miniature Appaloosa stallion presented with 6 months of history of sanguineous crusts on medial hind limbs and discomfort of micturition. Cauliflower-like and small masses were treated with cryotherapy for 6 months, but the regrowth of masses occurred. Subsequently, local excision via laser and topical treatment with 5% 5-fluorouracil for 5 months were followed. However, the horse was euthanized 4 months later due to regrowth of the masses. The mass was diagnosed as penile papilloma with cellular atypia and Equus caballus papillomavirus type 2 (EcPV-2) DNA was detected. This is the first report of equine penile neoplasm with EcPV-2 infection in Asia.

Keyword

penile papilloma; papillomavirus type 2; EcPV-2; Appaloosa; horses
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