Clin Endosc.  2024 Mar;57(2):277-279. 10.5946/ce.2024.016.

Whitish gastric mucosa on upper gastrointestinal endoscopy

• Gong EJ
• Bang CS

• KMID: 2553768
• DOI: http://doi.org/10.5946/ce.2024.016

Figure

• 

  Fig. 1. Endoscopic and histologic findings. (A–C) Diffuse whitish granular mucosa on the greater curvature side, posterior wall side of high body, and cardia on white-light imaging. (D) Diffuse whitish granular mucosa on the greater curvature side, posterior wall side of high body, and cardia on narrow-band imaging. (E, F) Histiocytes aggregating in superficial lamina propria (hematoxylin & eosin stain: E, ×100; F, ×200).

Reference

1. Albaaj F, Hutchison AJ. Lanthanum carbonate (Fosrenol): a novel agent for the treatment of hyperphosphataemia in renal failure and dialysis patients. Int J Clin Pract. 2005; 59:1091–1096.

2. Hutchison AJ, Wilson RJ, Garafola S, et al. Lanthanum carbonate: safety data after 10 years. Nephrology (Carlton). 2016; 21:987–994.

3. Makino M, Kawaguchi K, Shimojo H, et al. Extensive lanthanum deposition in the gastric mucosa: the first histopathological report. Pathol Int. 2015; 65:33–37.

4. Iwamuro M, Urata H, Tanaka T, et al. Review of the diagnosis of gastrointestinal lanthanum deposition. World J Gastroenterol. 2020; 26:1439–1449.

5. Kim SY, Lee JH, Lee SK. Gastric mucosal calcinosis. Korean J Gastroenterol. 2017; 70:208–210.

6. Kim GH. Proton pump inhibitor-related gastric mucosal changes. Gut Liver. 2021; 15:646–652.

7. Kim GH. Clinicians should be aware of proton pump inhibitor-related changes in the gastric mucosa. Clin Endosc. 2024; 57:51–52.

8. Kubo K, Kimura N, Kato M. Potassium-competitive acid blocker-associated gastric mucosal lesions. Clin Endosc. 2024; Feb. 29. [Epub]. https://www.doi.org/10.5946/ce.2023.279.

9. Nishida S, Ota K, Hattori K, et al. Investigation of the clinical significance and pathological features of lanthanum deposition in the gastric mucosa. BMC Gastroenterol. 2020; 20:396.

10. Nakamura T, Tsuchiya A, Kobayashi M, et al. M2-polarized macrophages relate the clearance of gastric lanthanum deposition. Clin Case Rep. 2019; 7:570–572.