J Vet Sci.  2024 Jan;25(1):e18. 10.4142/jvs.23147.

Basic concepts, recent advances, and future perspectives in the diagnosis of bovine mastitis

Affiliations
  • 1Engineering Laboratory for Tarim Animal Diseases Diagnosis and Control, College of Animal Science and Technology, Tarim University, Alar, Xinjiang 843300, China
  • 2Key Laboratory of Tarim Animal Husbandry & Science Technology of Xinjiang Production & Construction Corps., Alar, Xinjiang 843300, China
  • 3National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Wuhan, Hubei 430070, China
  • 4Department of Clinical Pathology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh 13736, QG, Egypt
  • 5The State Key Laboratory of Agricultural Microbiology, (HZAU), Wuhan, Hubei 430070, China
  • 6Department of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, University of Sadat City, Sadat City 32897, Egypt
  • 7MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan, Hubei 430070, China
  • 8Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western China, School of Life Sciences, Ningxia University, Yinchuan, Ningxia 750021, China
  • 9College of Integrated Chinese and Western Medicine, Southwest Medical University, Lu Zhou, Sichuan 646000, China

Abstract

Mastitis is one of the most widespread infectious diseases that adversely affects the profitability of the dairy industry worldwide. Accurate diagnosis and identification of pathogens early to cull infected animals and minimize the spread of infection in herds is critical for improving treatment effects and dairy farm welfare. The major pathogens causing mastitis and pathogenesis are assessed first. The most recent and advanced strategies for detecting mastitis, including genomics and proteomics approaches, are then evaluated . Finally, the advantages and disadvantages of each technique, potential research directions, and future perspectives are reported. This review provides a theoretical basis to help veterinarians select the most sensitive, specific, and cost-effective approach for detecting bovine mastitis early.

Keyword

Mastitis; pathogen; diagnosis; proteomics; protein biochips
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