Nutr Res Pract.  2024 Feb;18(1):78-87. 10.4162/nrp.2024.18.1.78.

Association of daily carbohydrate intake with intermuscular adipose tissue in Korean individuals with obesity: a cross-sectional study

• Choi HN
• Kim YS
• Yim JE

• KMID: 2552282
• DOI: http://doi.org/10.4162/nrp.2024.18.1.78

Abstract

BACKGROUND/OBJECTIVES
The prevalence of obesity, a worldwide pandemic, has been increasing steadily in Korea. Reports have shown that increased intermuscular adipose tissue (IMAT) is associated with an increased risk of cardiovascular disease, independent of body mass index. However, the relationship between dietary intake and IMAT accumulation in the Korean population remains undetermined. The objective of this study was to evaluate regional fat compartments using advanced magnetic resonance imaging (MRI) techniques. We also aimed to investigate the association between IMAT amounts and dietary intake, including carbohydrate intake, among Korean individuals with obesity.
SUBJECTS/METHODS
This cross-sectional study, performed at a medical center in South Korea, recruited 35 individuals with obesity (15 men and 20 women) and classified them into 2 groups according to sex. Anthropometry was performed, and body fat distribution was measured using MRI. Blood parameters, including glucose and lipid profiles, were analyzed using commercial kits. Linear regression analysis was used to test whether the IMAT was associated with daily carbohydrate intake.
RESULTS
Carbohydrate intake was positively associated with IMAT in all individuals, with adjustments for age, sex, height, and weight. No significant differences in blood indicators were found between the sexes.
CONCLUSIONS
Regardless of sex and age, higher carbohydrate intake was strongly correlated with greater IMAT accumulation. This suggests the need to better understand sex differences and high carbohydrate diet patterns in relation to the association between obesity and metabolic risk, which may help reduce obesity prevalence.

Keyword

Carbohydrates; dietary intake; adipose tissue; magnetic resonance imaging; obesity

Figure

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  Fig. 1 Covariates-adjusted partial correlation coefficients between daily carbohydrate intake and IMAT.IMAT, intermuscular adipose tissue.

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