Myosin Inhibitors Can Reduce Primary Mitral Regurgitation by Improving Systolic Anterior Motion of the Mitral Leaflets
- Affiliations
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- 1Department of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ, USA
- KMID: 2552229
- DOI: http://doi.org/10.4070/kcj.2023.0290
Figure
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Figure 1 Images showing the improvement of MR on Mavacamten.(A) Parasternal long axis image showing significant SAM. (B) Apical 4-chamber image showing severe anteriorly directed-MR. (C) Doppler image showing severe LVOT obstruction at rest of 5 m/s. (D) 3D TEE showing P2 scallop prolapse. (E) Image showing SAM along with leaflet coaptation gap exacerbated by SAM and severe, anteriorly directed MR jet. (F) Parasternal long axis image showing improvement of SAM on Mavacamten therapy. (G) Apical 4-chamber image with color compare showing mild-moderate residual MR on Mavacamten. (H) Doppler image of the LVOT showing no residual obstruction.LVOT = left ventricular outflow tract; MR = mitral regurgitation; SAM = systolic anterior motion; 2D = two dimensional; 3D = three dimensional.
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