J Oral Med Pain.
2023 Dec;48(4):131-136. 10.14476/jomp.2023.48.4.131.
Potential Biomarkers for an Evidence-Based Diagnosis of Burning Mouth Syndrome
- Affiliations
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- 1Department of Oral Medicine, Institute of Oral Bioscience, School of Dentistry, Jeonbuk National University, Jeonju, Korea
- 2Research Institute of Clinical Medicine of Jeonbuk National University - Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
- KMID: 2552100
- DOI: http://doi.org/10.14476/jomp.2023.48.4.131
Abstract
- Burning mouth syndrome (BMS), a chronic pain disorder with an unclear etiology, is characterized by a burning sensation in the oral cavity. The absence of objective diagnostic methods for this condition complicates its diagnosis and treatment. Recently, efforts have been ongoing to find biomarkers for the diagnosis and evaluation of patients with BMS. Several studies have reported hematological changes, differences in salivary protein composition, and peripheral neuropathy in the affected oral tissues. This review summarizes the research regarding the objective changes observed in patients with BMS to identify potential diagnostic approaches.
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