Korean J Transplant.  2023 Nov;37(Suppl 1):S292. 10.4285/ATW2023.F-9060.

Urinary tract infection in kidney transplant recipient at Prof. dr. I.G.N.G Ngoerah General Hospital, Bali, Indonesia

• Mahadita GW
• Widiana IGR
• Kandarini Y
• Ayu P

• KMID: 2551921
• DOI: http://doi.org/10.4285/ATW2023.F-9060

Abstract

Background
Kidney transplant recipients most often have urinary tract infections (UTIs). Surgical advances and immunosuppressive therapies have improved graft survival. However, infection problems have increased, causing concernenteric Gram-negative bacilli and enterococci cause posttransplant UTIs. Our study investigated UTI incidence and microbiological profile in renal transplant recipients at our institution.
Methods
Twenty-four kidney transplant patients at Prof. Dr. I.G.N.G Ngoerah General Hospital were studied for seven years from 2016 to 2023 in this prospective cohort study. UTI, culture results, and bacteria types were recorded for all kidney transplant patients.
Results
The average age of the 24 participants was 34 (9.36) years (17 males [70.8%], 7 females [29.2%]). The incidence of UTIs over 7 years reached 70.8% (37.5% for primary UTI and 33.3% for recurrent UTI). The entire UTI patients have gram-negative infections, with only two (11.8%) exhibiting gram-positive infections. Klebsiella pneumoniae (30.7%), Enterobacter (30.7%), Pseudomonas (15.38%), and Escherichia coli (11.54%) were the most prevalent causes of all bacterial infection episodes (26 infection episodes in all samples). The incidence of UTI was found to be greater in females (85.7%) than in males (64%). One hundred percent of K. pneumoniae exhibited multidrug resistance. The median duration of urinary catheter use was 10 days (range, 7–30 days), and we observed a higher incidence of UTI in patients with urinary catheter use durations exceeding 10 days, with a relative risk of 1.5 (95% CI, 0.54–4.12).
Conclusions
At Prof. dr. I.G.N.G. Ngoerah General Hospital, 70.8% of kidney transplant patients suffered from urinary tract infections. There were no gram-positive bacteria and only 11.8% gram-negative bacteria present. K. pneumoniae with multidrug resistance was the most prevalent causative microorganism.