Korean J Transplant.  2023 Nov;37(Suppl 1):S283. 10.4285/ATW2023.F-8980.

Indication and survival among liver transplant patients in Yangon Speciality Hospital, Myanmar

• Yin HA
• Mar TT
• Sai Aung SA

• KMID: 2551912
• DOI: http://doi.org/10.4285/ATW2023.F-8980

Abstract

Liver transplantation has become the standard of treatment for various liver diseases such as end stage liver disease from various etiologies and early stages of hepatocellular carcinoma (HCC). The major goals of liver transplantation are to prolong life expectancy and to improve quality of life. In Myanmar, the first liver transplantation was successfully performed in 2004 by Dr. Norman Hla, Professor of Surgery who pioneered in liver transplantation of our country. In 2016, collaborated liver transplantation program with Korean liver transplant surgeons was implemented in Yangon Speciality Hospital. From October 2016 to December 2019, a total 30 of adult liver transplantation has been performed in Department of Hepatobiliary and Pancreatic Surgery, Yangon Speciality Hospital. Indications for liver transplantation includes 20 cases of HCC, nine cases with cirrhosis from chronic liver diseases and one case with Budd-Chiari syndrome. Among 30 patients, hepatitis B and C infected patients are 25 cases and only five cases are non B, non C. One year survival rate and graft survival rates are 73% and 80%, respectively. The best survival has been shown to occur among patients underwent liver transplant for cirrhosis with chronic liver disease and the worst survival occurred in patients with HCC. No donor mortality or transplant related morbidity account in our center experience. The prevalence of hepatitis B and C are high in Myanmar and genotype of hepatitis B virus (HBV) among Myanmar patients is high associated with HCC, therefore HBV and hepatitis C virus related chronic liver failure and HCC are increasing. As liver transplant becomes the standard of treatment for chronic liver disease, patients needing liver transplant as the definitive treatment of their diseases on the other hand. Therefore. strong multidisciplinary teams for liver transplant program are needed for future of our country and also national strategies for elimination of hepatitis B and C should be much more promoted.