Korean J Transplant.  2023 Nov;37(Suppl 1):S129. 10.4285/ATW2023.F-7120.

Urinary tract infection incidence, risk factors and impact on short term outcome in kidney transplant recipients in Mongolia

• Tseren K
• Lkhakhuu OE
• Dагвадорж BU

• KMID: 2551749
• DOI: http://doi.org/10.4285/ATW2023.F-7120

Abstract

Background
According to literature review, incidence of urinary tract infection (UTI) which is one of the most common infectious complications in kidney transplant recipients was 25%–75%. The incidence is related to various factors including age, gender difference, immunosuppression type and amount and kidney function. Moreover, UTI may deteriorate graft function. However, there was lack of data addressing impact of UTI on patient and graft survival.
Methods
From 2015 to 2022, a total of 198 patients who received living kidney transplants at the First Central Hospital of Mongolia participated in this study. We divided study participants into two groups regarding whether diagnosed with UTI. Participants demographic data, comorbidity, kidney function and immunosuppression data were collected. Moreover, we evaluated the patients 1- and 3-years survival rate by study two groups. We also considered short term outcome as acute pyelonephritis, sepsis and graft failure. All analyses were performed using STATA 17.
Results
Study participants mean age was 42±12 years and 76.8% were male. Of the 198 patients, 58 patients (29.3%) suffered from UTI. Increasing age, female patients and taking high dose of immunosuppression were regarded as independent risk factors leading to UTI. Compared to control group, patients with UTI had higher risk of worsening graft function at discharge. Ciprofloxacin and nitrofurantoin are most commonly prescribed antibiotics.
Conclusions
UTIs are one of the main causes of graft dysfunction. Therefore, prevention and effective management of UTI are crucial in practice of renal transplantation.