Korean J Transplant.  2022 Nov;36(Supple 1):S144. 10.4285/ATW2022.F-2632.

COVID-19 infection outcomes of the kidney transplant recipients in Mongolia

• Tseren K
• Lkhaakhuu O
• Dagvadorj B

• KMID: 2535660
• DOI: http://doi.org/10.4285/ATW2022.F-2632

Abstract

Background
The number of deaths due to the COVID-19 pandemic is 649.9 per 1 million people globally, and 542 cases per 1 million people are recorded in Mongolia. This study was conducted because the prognosis of kidney transplant recipients after treatment for COVID-19 infection has not been studied in Mongolia.
Methods
This study was held between period from March 15, 2021 to Nov 1, 2021 in the Transplantation Center of First Central Hospital. Of 278 recipients, 105 (37.7%) kidney transplant patients were confirmed to have COVID-19 infection.
Results
Out of 278 kidney transplantation recipients, 239 (85.9%) were from living donors and 39 (14%) were from diseased donors. From total infected recipients 35.5% are living donors and 51% diseased donors was a statistically significant differ-ence (P<0.001). The average age was 43.5±9.2, 33.4% were over 50 years old and 70.5% were male. 48.3% diabetes recipients were infected with COVID-19, which was the leading risk of underlying disease (P<0.001). Recipients were immunized with the M-RNA-based Pfizer vaccine, and four out of five unvaccinated recipients was infected COVID-19, 12 out of 19 got the first dose, 79 out of 95 got the second dose, and 10 out of 159 got the third dose, had confirmed COVID-19 infection. Recipients who received three doses of immunization had a lower risk of COVID-19 infection, whereas four out of five (80%) of unimmunized recipients died, showing a vaccine effectiveness (P<0.001). There were 33 (31.4%) cases of lung pneumonia and eight (7.6%) kidney injury reported due to the infection.
Conclusions
The recipients of the kidney transplantation with confirmed COVID-19 infection are over 50 years old, unimmu-nized, underlying diseases, and immunosuppression are risk factors for complication of disease and affecting the future prog-nosis.