Med Lasers.  2023 Mar;12(1):51-58. 10.25289/ML.23.003.

Effectiveness of 250-picosecond laser for the treatment of melasma and pigmented lesions with a low fluence 1,064-nm Nd:YAG laser in Republic of Korea: retrospective study

• Lee SJ
• Kim DG
• Nam SM
• Cha HG
• Park ES

• KMID: 2551128
• DOI: http://doi.org/10.25289/ML.23.003

Abstract

Background
Melasma is a pigment disease mainly acquired by skin exposed to sunlight. Picosecond laser was developed for a treatment that is more effective than Q-switch laser in tattoo treatment and can reduce complications. This study was undertaken to confirm the efficacy of a 250-picosecond laser in melasma and pigmented lesion therapy.
Methods
The study is a retrospective analysis of melasma and pigmented lesion cases treated from April 2022 to September 2022 using the 250-picosecond 1,064-nm laser. Data before and after treatment were compared for patients who had undergone picosecond lasers toning mode up to five times. A clinical picture of the patient was taken using skin analysis program, and quantitative values for skin pigment and skin tone were obtained.
Results
A total of 87 patients were included in the study. Results of the paired-sample t-test comparing the difference in polarized light and ultraviolet pigmentation in entirety and for each part showed a decrease in the mean score. Analysis of skin tone revealed that a higher score showed better results. The mean score of skin tone increased statistically significantly.
Conclusion
Our results confirmed that the 250-picosecond laser is effective in treating melasma and pigmented lesions. In particular, our study used a skin analysis tool program to add objectivity and confirmed the statistical significance of the results.

Keyword

Pico toning; Picolasers; Laser therapy; Pigmentation; Melanosis