Exp Neurobiol.
2023 Dec;32(6):371-386. 10.5607/en23040.
Arcuate Nucleus of the Hypothalamus: Anatomy, Physiology, and Diseases
- Affiliations
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- 1Department of Anatomy, Chonnam National University Medical School, Hwasun 58128, Korea
- 2Department of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Korea
- KMID: 2550807
- DOI: http://doi.org/10.5607/en23040
Abstract
- The hypothalamus is part of the diencephalon and has several nuclei, one of which is the arcuate nucleus. The arcuate nucleus of hypothalamus (ARH) consists of neuroendocrine neurons and centrally-projecting neurons. The ARH is the center where the homeostasis of nutrition/metabolism and reproduction are maintained. As such, dysfunction of the ARH can lead to disorders of nutrition/metabolism and reproduction. Here, we review various types of neurons in the ARH and several genetic disorders caused by mutations in the ARH.
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