Investig Clin Urol.  2024 Jan;65(1):1-8. 10.4111/icu.20230265.

2023 Korean Association of Urogenital Tract Infection and Inflammation guidelines for gonococcal infection

Affiliations
  • 1Department of Urology, Soonchunhyang University College of Medicine, Cheonan, Korea
  • 2Department of Laboratory Medicine, Yonsei University, Seoul, Korea
  • 3Department of Urology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
  • 4Department of Urology, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea
  • 5Department of Urology, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea
  • 6Department of Urology, Yonsei University Wonju College of Medicine, Wonju, Korea
  • 7Center of Evidence-Based Medicine, Institute of Convergence Science, Yonsei University, Seoul, Korea
  • 8Department of Urology, Chonnam National University Medical School, Gwangju, Korea

Abstract

The incidence of gonorrhea has increased significantly in recent years in the United States, especially among sexually active twenty-year-olds. Although the incidence of gonorrhea has decreased in Korea since the early 2000s, it is still common among people in their twenties. Nucleic acid amplification test (NAAT) is the most sensitive diagnostic test for detecting gonococcal infection. Gram-staining is a simple and useful laboratory test for diagnosing symptomatic male gonococcal urethritis. Although bacterial culture can be used to detect antimicrobial susceptibility, its sensitivity is lower than that of NAAT. Treatment for uncomplicated gonorrhea infection is a single intramuscular injection of ceftriaxone 500 mg. Doxycycline (100 mg twice daily for 7 days) is added if there is a possibility of co-infection with chlamydia. If ceftriaxone is difficult to use, spectinomycin 2 g can be injected intramuscularly in Korea. Patients with gonorrhea should have repeated examinations within three months at the exposure site because of a high risk of re-infection. A person diagnosed with gonorrhea should discuss the nature of the infection, the importance of informing partners, when sexual activity can resume, and how to reduce the risk of sexually transmitted infections.

Keyword

Guideline; Neisseria gonorrhoeae; Sexually transmitted diseases
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