Korean J Blood Transfus.
2023 Dec;34(3):211-213. 10.17945/kjbt.2023.34.3.211.
Report on Unexpected Antibodies Detected Exclusively in the Serum
- Affiliations
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- 1Department of Laboratory Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea
- KMID: 2549683
- DOI: http://doi.org/10.17945/kjbt.2023.34.3.211
Abstract
- In 2023, an 81-year-old woman requested a preliminary red blood cell transfusion during pancreatic cancer surgery, and antibody screening was performed using automated blood typing equipment. The antibody screening test results were negative when plasma was used as the sample but positive when the serum was used instead. The 4℃ test was positive when using the enzyme method but negative at warm temperatures. An unknown antibody was identified using a commercial antibody identification test (Bio-Rad, CA, USA). A clinically insignificant cold antibody was detected only in the serum samples, and the negative blood was ultimately released following the third stage of cross-matching using anti-human globulin.
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