J Dig Cancer Res.  2023 Dec;11(3):157-164. 10.52927/jdcr.2023.11.3.157.

Development and Validation of a Prediction Model: Application to Digestive Cancer Research

Affiliations
  • 1Department of Biostatistics and Computing, Yonsei University Graduate School, Seoul, Korea
  • 2Department of Radiology, Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea

Abstract

Prediction is a significant topic in clinical research. The development and validation of a prediction model has been increasingly published in clinical research. In this review, we investigated analytical methods and validation schemes for a clinical prediction model used in digestive cancer research. Deep learning and logistic regression, with split-sample validation as an internal or external validation, were the most commonly used methods. Furthermore, we briefly introduced and summarized the advantages and disadvantages of each method. Finally, we discussed several points to consider when conducting prediction model studies.

Keyword

Machine learning; Clinical decision rules; Precision medicine
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