Pediatr Emerg Med J.  2024 Jan;11(1):51-56. 10.22470/pemj.2023.00822.

Obscure gastrointestinal bleeding in a patient with factor VII deficiency: a case controlled with tranexamic acid

• Jeong KH
• Choi YB
• Kim YB

• KMID: 2549541
• DOI: http://doi.org/10.22470/pemj.2023.00822

Abstract

Factor VII deficiency is a rare, inherited coagulopathy, which can lead to prolonged bleeding. Here, we present a case report of an adolescent with factor VII deficiency who experienced small bowel bleeding that was successfully treated with tranexamic acid. This case highlights the potential use of tranexamic acid as an effective therapeutic option for managing gastrointestinal bleeding in patients with hemostatic insufficiency of unknown etiology.

Keyword

Blood Coagulation Disorders; Blood Coagulation Factors; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Tranexamic Acid

Figure

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  Fig. 1. Esophagogastroduodenoscopy finding (day 1) of no evident gastric and duodenal involvement (A). Colonoscopy finding of bleeding with a clot (not shown) from an uncertain focus (B).

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  Fig. 2. Capsule endoscopic findings (day 4) showing no evident proximal small bowel involvement (A) and blood-tinged mucosa on the distal ileum (B).

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  Fig. 3. A follow-up colonoscopic findings (day 4). After biopsy, bleeding from an uncertain focus is seen on the terminal ileum even after applying an epinephrine spray (A) with substantial oozing blood flowing to the cecum via the ileocecal valve (B).

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  Fig. 4. Trend of hemoglobin.

Reference

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