J Vet Sci.  2023 Nov;24(6):e78. 10.4142/jvs.23105.

Evolution and international transmission of H3N2 canine influenza A viruses from Korea during 2014–2017

Affiliations
  • 1Department of Microbiology, School of Medicine, Kyungpook National University, Daegu 41944, Korea

Abstract

Avian-origin H3N2 canine influenza A viruses (CIVs) have become enzootic in China and Korea and have sporadically transmitted to North America, causing multiple epidemics. We isolated six CIVs in Korea from CIV-infected patients during 2014–2017 and conducted whole genome sequencing and phylogenetic analyses. Results revealed that CIVs have circulated and evolved in Korea since the early 2000s and then diversified into a new clade, probably contributing to multiple epidemics in China, the USA, and Canada. Our findings bridge an evolutionary gap for understanding the global transmission of CIVs, emphasizing the significance of continuous monitoring of CIVs.

Keyword

H3N2 virus; phylogenetic analysis; infectious disease transmission; molecular evolution
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