Ann Dermatol.  2023 Nov;35(Suppl2):S215-S218. 10.5021/ad.21.083.

Distant Metastatic Microcystic Adnexal Carcinoma

• Lee SH
• Yun SY
• Yu DS
• Lee YB

• KMID: 2548846
• DOI: http://doi.org/10.5021/ad.21.083

Abstract

Microcystic adnexal carcinoma (MAC) is a rare malignant neoplasm of ductal origin. MAC is a clinically aggressive, locally destructive tumor with a high rate of recurrence, but distant metastasis is rare. A 55-year-old male who had been taking immunosuppressants for 2 years after a liver transplantation due to hepatocellular carcinoma presented with a dermal nodule on the sole. He visited the clinic because the nodule, discovered 3 months ago, continued to increase in size. The histopathologic findings from the lesion were consistent with MAC. The patient underwent wide local excision and confirmed a histologically negative margin. After 11 months, the patient revisited with multiple skin nodules on the buttock, back, and right forearm that were distant from the primary tumor site. The lesions were histologically confirmed as MAC. We report a rare case of MAC with distant metastasis.

Keyword

Microcystic adnexal carcinoma; Neoplasm metastasis