J Korean Med Sci.  1994 Oct;9(5):432-435. 10.3346/jkms.1994.9.5.432.

Combined microcystic adnexal carcinoma and squamous cell carcinoma arising in the ovarian cystic teratoma: a brief case report

Affiliations
  • 1Department of Pathology, Pusan Paik Hospital, Inje University, Pusanjin-gu, Korea.

Abstract

Malignant transformation of mature cystic teratoma of the ovary can develop with an incidence of 1-2%. Squamous cell carcinoma is the most common malignant tumor arising in benign cystic teratoma. The authors have recently experienced a case of combined microcystic adnexal carcinoma and squamous cell carcinoma arising in a benign cystic teratoma of the ovary in a 72-year-old Korean woman. The right ovarian cystic mass had been ruptured and firmly adhered with salpinx and omental fat tissue on operation. Thickened cystic wall with yellowish white solid infiltrative lesion was noted grossly, and two different malignant tumors of microcystic adnexal carcinoma exhibiting both eccrine and hair follicular differentiation and squamous cell carcinoma were observed microscopically. PAS and CEA positivities suggested eccrine differentiation in areas of microcystic adnexal carcinoma.

Keyword

microcystic adnexal carcinoma; squamous cell carcinoma; Cystic teratoma; Ovary

MeSH Terms

Aged
Carcinoma, Skin Appendage/*pathology
Carcinoma, Squamous Cell/*pathology
Case Report
Female
Human
Neoplasms, Multiple Primary/*pathology
Ovarian Neoplasms/*pathology
Skin Diseases/*pathology
Skin Neoplasms/*pathology
Teratoma/*pathology
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