Clin Psychopharmacol Neurosci.
2023 Nov;21(4):665-675. 10.9758/cpn.23.1058.
Brain Neuroplasticity after Treatment with Antiseizure: A Review
- Souza DLSd
1 - Costa HMGeS2
- Neta FI1
- Morais PLAdG1
- Guerra LMdM1
- Guzen FP1
- Oliveira LCd2
- Cavalcanti JRLdP1
- Albuquerque CCd3
- Vasconcelos CLd4
- Affiliations
-
- 1Faculty of Health Sciences, Department of Biomedical Sciences, Universidade do Estado do Rio Grande do Norte, Mossoró, Brazil
- 2Faculty of Nursing, Department of Nursing, Universidade do Estado do Rio Grande do Norte, Mossoró, Brazil
- 3Faculty of Exact and Natural Sciences, Department of Biological Sciences, Universidade do Estado do Rio Grande do Norte, Mossoró, Brazil
- 4Faculty of Exact and Natural Sciences, Department of Chemistry, Universidade do Estado do Rio Grande do Norte, Mossoró, Brazil
- KMID: 2548812
- DOI: http://doi.org/10.9758/cpn.23.1058
Abstract
- Epilepsy is a disease characterized by the periodic occurrence of seizures. Seizures can be controlled by antiseizure medications, which can improve the lives of individuals with epilepsy when given proper treatment. Therefore, this study aimed to review the scientific literature on brain neuroplasticity after treatment with antiseizure drugs in different regions of the brain. According to the findings, that several antiseizure, such as lamotrigine, diazepam, levetiracetam, and valproic acid, in addition to controlling seizures, can also act on neuroplasticity in different brain regions. The study of this topic becomes important, as it will help to understand the neuroplastic mechanisms of these drugs, in addition to helping to improve the effectiveness of these drugs in controlling the disease.
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