Korean J Head Neck Oncol.  2023 Nov;39(2):41-44. 10.21593/kjhno/2023.39.2.41.

A Case of Follicular Dendritic Cell Sarcoma in Submandibular Region

• Yoo JH
• Lee DW
• Kim JK

• KMID: 2548693
• DOI: http://doi.org/10.21593/kjhno/2023.39.2.41

Abstract

Follicular dendritic cell sarcoma (FDCS) is rare lymphoid sarcoma occurs anywhere in body, mostly in lymph nodes. Sixty-two-year-old man presented left submandibular gland region mass for 5 months. Mass excision with submandibular gland resection was performed. Histopathology showed proliferation of spindle and ovoid cells with storiform arrangement which were positive for CD21, CD23, Vimentin, Ki-67, suggested FDCS in submandibular gland region lymph node. Tumor size was 3cm with no involvement of resection margin, nor cellular atypia and necrosis, so regular follow up was performed. After 4 years, new enhancing mass in left submandibular area was found. Wide excision of mass with neck dissection on left level I-III was performed. Histopathology confirmed recurrence of FDCS. The patient underwent radiation therapy from left mandible to hyoid area. After 2 years, new nodule was found in left lung upper lobe, and wedge resection confirmed metastasis of FDCS. The patient is on adjuvant chemotherapy.

Keyword

Follicular dendritic cell sarcoma⋅Salivary gland tumor